水貂犬瘟热Vero细胞活疫苗保存期试验研究  

Study on Storage Period of Mink Canine Distemper Live Vaccine of Vero Cell Culture

作　　者：柴秀丽[1] 丛丽[1] 闫喜军[1] 吴威[1] 赵传芳[1] 罗国良[1] 

机构地区：[1]中国农业科学院特产研究所,吉林吉林132109

出　　处：《特产研究》2007年第4期11-12,15,共3页Special Wild Economic Animal and Plant Research

基　　金：科技部科研院所社会公益研究专项(2005DIB4J048)

摘　　要：对-20℃保存90d、120d、150d、180d、210d、240d、300d的水貂犬瘟热Vero细胞活疫苗的病毒含量以及疫苗免疫试验进行测定。结果表明,保存180d的疫苗病毒含量基本保持不变,保存240d疫苗病毒含量有所下降;疫苗免疫240d中和抗体仍在临界保护值1:40以上,确定该疫苗在-20℃条件下保存期为180d。The virus titer and antibody level of inoculated minks for mink canine distemper live vaccine of vero cell culture which were stored in the 90d.120d,150d,180d.210d,240d and 300d at -2022 were tested,the result showed the virus titer of the 180d were maintained and dropped slowly;the SN antibody titer was still above 1 ： 40 after minks were inoculated for the 240d, so the storage period of mink canine distemper live vaccine of vero cell culture was the 180d at -20℃.

关 键 词：水貂 犬瘟热 VERO细胞 活疫苗 保存期 

分 类 号：S865.22[农业科学—野生动物驯养] S852.65[农业科学—畜牧兽医]