扩张性心肌病患者心率震荡的变化  

Study of heart rate turbulence in patients with dilated cardiomyopathy

作　　者：葛健[1] 邓汉华[1] 盛利华[1] 陈葵[1] 

机构地区：[1]武汉大学人民医院心内科,湖北武汉430060

出　　处：《心血管康复医学杂志》2007年第6期593-594,共2页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:观察扩张型心肌病(DCM)患者心率震荡(HRT)的变化。方法:选择DCM患者47例,正常健康对照者50例,运用24h动态心电图记录资料,计算HRT的两个参数震荡初始(TO)和震荡斜率(TS),比较两组之间的差别。结果:DCM组TO值显著高于对照组[(2.14±0.57)%:(0.73±0.65)%,P<0.05];DCM组TS值显著低于对照组[(2.34±0.81):(4.09±1.32)ms/RR间期,P<0.05]。结论:扩张型心肌病患者室性早搏后的HRT现象减弱,说明其自主神经功能明显受损。HRT可作为评价扩张型心肌病患者自主神经功能状态,判定预后的一项指标。Objective： To investigate the heart rate turbulence in patients with dilated cardiomyopathy （DCM）. Methods： The 47 DCM patients （DCM group） and 50 normal controls （control group） were examined by 24 h Holter monitoring and compared HRT parameters as turbulence onset （TO） and turbulence slope （TS） between DCM group and control group. Results： The HRT parameters showed significant differences in two group： Turbulence onset of DCM [ （2. 14±0. 57）%] was more than that of controls [ （0.73±0.65） %], P〈0. 05; Turbulence slope of DCM [ （2. 34±0. 81） ms/RR] was less than that of controls [ （4.09±1.32） ms/RR], P〈0.05. Conclusion： Attenuation of heart rate turbulence in patients with dilated cardiomyopathy after ventricular premature beats demonstrate that the function of autonomic nerve of DCM patients has been impaired significantly and HRT can be viewed as a method applied in risk stratification of the function of autonomic nerve and evaluating prognosis in DCM patients.

关 键 词：心肌病 扩张型 心率 心电图描记术 便携式 

分 类 号：R542.2[医药卫生—心血管疾病]