Quality Control of 1-Alkyl-3-methylimidazolium Ionic Liquid Precursors with HPLC  

作　　者：张延强 张建敏 陈玉涣 张锁江 

机构地区：[1]State Key Laboratory of Multi-phase Complex System,Institute of Process Engineering,Chinese Academy of Sciences

出　　处：《过程工程学报》2007年第6期1094-1098,共5页The Chinese Journal of Process Engineering

摘　　要：A high performance liquid chromatography(HPLC) method was proposed to monitor the synthesis and purification of the 1-alkyl-3-methylimidazolium ionic liquid precursors from alkylation of 1-methylimidazole with alkyl halides and determine the purity of final products.The results showed that separation of 1-methylimidazole from the precursors could be obtained under the HPLC performance conditions such as cation exchange column,acetonitrile/KH2PO4 aqueous solution and 209 nm wavelength.The content of unreacted 1-methylimidazole in the precursors could be easily calculated from their corresponding HPLC peak areas with the calibration curve of 1-methylimidazole.The retention times of the 1-alkyl-3-methylimidazolium ionic liquid precursors decreased with their increasing alkyls,and the ionic liquids with the same cation and different anions had almost the same retention times.A high performance liquid chromatography （HPLC） method was proposed to monitor the synthesis and purification of the 1-alkyl-3-methylimidazolium ionic liquid precursors from alkylation of 1-methylimidazole with alkyl halides and determine the purity of final products. The results showed that separation of 1-methylimidazole from the precursors could be obtained under the HPLC performance conditions such as cation exchange column, acetonitrile/KH2PO4 aqueous solution and 209 nm wavelength. The content of unreacted 1-methylimidazole in the precursors could be easily calculated from their corresponding HPLC peak areas with the calibration curve of 1-methylimidazole. The retention times of the 1-alkyl-3-methylimidazolium ionic liquid precursors decreased with their increasing alkyls, and the ionic liquids with the same cation and different anions had almost the same retention times.

关 键 词：质量控制 1-烃基-3-甲基咪唑 液相色谱 离子性液体 前体 纯度 1-甲基咪唑 

分 类 号：TQ252.3[化学工程—有机化工]