肛肠病术后两种长效止痛剂镇痛效果的临床研究  

Clinical Study on the Analgesic Effect of Two Long-acting Analgesics Applied after Anorectal Operations

作　　者：席作武[1] 张英[2] 李相臣[3] 牛明了[3] 刘小文[3] 

机构地区：[1]河南省中医院肛肠科,河南郑州450002 [2]河南省直机关第一门诊部 [3]河南中医学院中医外科学研究生

出　　处：《中国肛肠病杂志》2007年第11期39-41,共3页Chinese Journal of Coloproctology

基　　金：本课题为河南省科技攻关项目（496060403）

摘　　要：为探讨以亚甲蓝为主的两种长效止痛剂对肛肠病术后临床镇痛的效果及机理，将肛肠病术后210例分为A组（亚甲蓝、布比卡因配比）100例、B组（亚甲蓝、利多卡因配比）60例和对照组（口服去痛定、舒乐安定片）50例，采用VAS评分法，在术后6～120h分别观察其术后镇痛效果。结果显示，A组与对照组6～120hVAS评分和镇痛效果有非常显著性差异（P〈0．01）；A组和B组术后6hVAS评分和镇痛效果差异有统计学意义（P〈0．05），24～120h差异无统计学意义（P〉0．05）。结果表明，亚甲蓝与布比卡因配比用于肛肠病术后镇痛效果很好，可以达到完全无痛。The objective of this study was to evaluate the analgesic results of two long-acting analgesics applied after anorectal operations. Two hundreds and ten patients were divided into 3 groups： 100 patients in group A received methylene blue plus bupivacaine as analgesics,60 patients in group B methylene blue plus lidocaine,and 50 patients in group C（the control group） oral piminodine and estazolam. The analgesic effects were observed and evaluated during the postoperative 6-120 hours with VAS score. As results, the VAS score and analgesic effects （postoperative 6-120 hours） had very notable difference statistically between group A and C（P 〈0.01）,while that （postoperative 6 hours） had statistical difference between group A and B（P 〈0. 05） and that （postoperative 24-120 hours） had no statistical difference between group A and B（ P 〉0.05）. It is concluded that methylene blue plus bupivacaine have a very good analgesic effects applied after anorectal operations.

关 键 词：肛肠疾病 长效止痛剂 镇痛 

分 类 号：R971.2[医药卫生—药品]