大孔吸附树脂对莲子心中有效成分的分离纯化研究  

Isolation and purification of effective components in Plumula Nelumbinis by macroporous adsorption resins

作　　者：张吉祥[1] 冯冬然[1] 欧来良[2] 

机构地区：[1]廊坊师范学院化学系,河北廊坊065000 [2]生物活性材料教育部重点实验室,南开大学,天津300071

出　　处：《中草药》2007年第12期1812-1814,共3页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(29974015);廊坊师范学院科学研究项目(LS200513);南开大学创新基金项目

摘　　要：目的研究大孔吸附树脂吸附分离莲子心中莲心碱、异莲心碱及甲基莲心碱的工艺条件及参数。方法考察了AKS-W、AB-8和H214树脂对莲心碱、异莲心碱及甲基莲心碱的静态及动态吸附性能,并采用HPLC定量分析莲心碱、异莲心碱及甲基莲心碱。结果AKS-W树脂对莲子心中有效成分有较好的吸附分离效果,提取物中莲心碱、异莲心碱及甲基莲心碱的质量分数分别提高到10.2%、6.7%和11.9%。结论大孔型非极性吸附树脂AKS-W对莲子心中有效成分是一种较为理想的分离介质。Objective To investigate the adsorption function of macroporous adsorption resins for the separation and purification of the effective components in Plumula Nelumbinis. Methods AKS-W, AB-8, and H214 resins were systematically studied for their adsorption capability, and the contents of the liensinine, isoliensinine, and neferine were determined by HPLC. Results AKS-W Resin had a preferable adsorptive and separateive effect for the effective components in Plumula Nelumbinis. The products containing 10.2%liensinine, 6.7% isoliensinine, and 11.9% neferine could be obtained. Conclusion Macroporous-type and non-polar adsorption resin AKS-W is an ideal adsorbent for the extraction of the effective components in Plumula Nelumbinis.

关 键 词：莲子心 莲心碱 异莲心碱 甲基莲心碱 大孔吸附树脂 

分 类 号：R284.2[医药卫生—中药学] R286.02[医药卫生—中医学]