伏毛铁棒锤地上部分生物碱成分研究  被引量:38

Studies on the Alkaloids of the Flower, Stem, Leaf of Yellow Monkshood(Aconitum flavum)

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作  者:李洪刚[1] 杨建萍[2] 田义杰[2] 赵毅军[2] 

机构地区:[1]大连市第三人民医院,116037 [2]甘肃省医学科学研究院

出  处:《中草药》1997年第5期265-266,共2页Chinese Traditional and Herbal Drugs

摘  要:首次从优毛铁棒锤Aconilumflavum地上部分(花、茎、叶)中分离出4个生物碱结晶。经鉴定晶Ⅰ为脱氧乌头碱(deoxyaconitine),晶Ⅱ为3-乙酰乌头碱(3-acetylaconitine),晶Ⅲ为乌头碱(aconitine),晶Ⅳ待鉴定。乌头碱的收率为0.12%(块根中乌头碱收率为0.20%),薄层层析鉴定地上部分与块根的生物碱基本一致,为开发3-乙酰乌头碱寻找了新的资源。Four alkaloids were isolated from the flower,stem and leaf of Aconitum flevum Hand-Mazz. for the first time. Three of them were identified as deoxyaconitine, 3-acetylaconitine and aconitine respectively by physicochemical constants and spectroscopic analysis. The other one needs to be identified. The yield of aconitine is 0.12% (aconitine of root is 0. 20% ). By TLC, alkaloids present in the flower, stem and leaf are same as that found in the root. There fore, the aerial parts of the plant may be exploited as a new source of 3-acetylaconitine.

关 键 词:伏毛铁棒锤 生物碱 地上部分 

分 类 号:R284.1[医药卫生—中药学]

 

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