急性荨麻疹患者血清肌酸激酶测定及其临床意义  

Serum Level of Creatine Kinase and Its Clinical Significance in Acute Urticaria

作　　者：李慧忠[1] 唐浩熙[2] 刘翔[1] 练霭云[1] 陈波[1] 金少芬[1] 缪志辉[1] 

机构地区：[1]暨南大学第五附属医院 广东省清远市人民医院皮肤科,广东清远511500 [2]暨南大学第五附属医院 广东省清远市人民医院检验科,广东清远511500

出　　处：《中国皮肤性病学杂志》2007年第12期735-736,共2页The Chinese Journal of Dermatovenereology

基　　金：2002~2003年度中华医学会皮肤性病学分会皮肤科研究基金

摘　　要：目的探讨急性荨麻疹患者血清肌酸激酶水平的变化及其临床意义。方法测定176例急性荨麻疹患者及128例健康人血清肌酸激酶水平。结果急性荨麻疹患者血清肌酸激酶水平明显高于对照组(P<0.001),其中尤以伴有发热和心肌损伤者升高更为明显。结论急性荨麻疹患者血清肌酸激酶水平明显升高,这可能与皮肤炎症反应有关。伴发热和心肌损伤者升高更明显。Objective To investigate the change of serum creatine kinase （CK） level and its clinical significance in acute urticaria. Methods Serum CK content was detected in 176 patients with acute urticaria and 128 healthy controls. Results Serum concentration of CK was significantly higher in patients than that in controls （P 〈 0. 001 ）, especially in those with pyrexia and myocardial damage. Conclusion There exists the upregulation of serum CK level in patients with acute urticaria,which could be originated from the febricity, myocardial damage and cutaneous inflammation.

关 键 词：荨麻疹 肌酸激酶 心肌损伤 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]