医院获得性肺炎发病机制的研究进展  

Study Progress about Pathogenesis of Hospital-acquired Pneumonia

作　　者：吴升[1] 郑赟[1] 王选锭[2] 

机构地区：[1]中国人民解放军第一一七医院,杭州310013 [2]浙江大学第二附属医院,杭州310000

出　　处：《医学综述》2007年第15期1141-1143,共3页Medical Recapitulate

摘　　要：医院获得性肺炎的发生必须是宿主与微生物间的平衡向有利于细菌定植和向下呼吸道侵袭的方向发展,反流和误吸导致上消化道和口咽部定植菌被吸入到下呼吸道是医院获得性肺炎的重要原因。医院获得性肺炎具有很高的发病率和病死率,了解其发病机制对于指导临床诊断治疗有很重要的意义。Hospital-acquired pneumonia（HAP） often results from the balance between host and microorganism, which is hdpful for microorganism to colonize and invade to lower respiratory tract. Field planting bacterium of upper gastrointestinal tract and pharynx oralis absorpted into lower reapiratory tract resulting from-reflowing and aspiration is the important causes for HAP. HAP has high disease rate and case fatality, studying its pathogenesis has important significance to guide its clinical diagnosis and therapy.

关 键 词：医院获得性肺炎 发病机制 定植菌 

分 类 号：R563.1[医药卫生—呼吸系统]