近红外无损伤脑血氧监测仪的研制——系统设计及实验验证  

Development and Validation of Near-infrared Brain Blood-Oxygen Monitor

作　　者：秦钊[1] 李凯扬[1] 杨宣东[1] 刘利军[1] 谢则平[2] 

机构地区：[1]武汉大学物理科学与技术学院生物医学物理研究室,武汉430072 [2]华中科技大学生命科学与技术学院生物医学工程研究室,汉430074

出　　处：《生物医学工程学杂志》2007年第6期1220-1223,共4页Journal of Biomedical Engineering

基　　金：武汉市科技型中小企业创新基金资助项目(武财[2005]84号)

摘　　要：我们设计并研制了一种脑血氧监测仪,利用近红外光谱检测生物组织血、氧含量的原理,实现了对双侧脑组织局部血、氧参数的同时检测。检测探头采用两个不同波长的超高亮LED作为光源,通过两个光电传感器分别接收经左右大脑组织散射后的光信号,实现双探头检测双侧脑组织局部血、氧参数检测的功能。而且检测探头的外型结构经过特殊设计,有效地抑止了外界环境噪声同时减小了固定检测探头时给病人带来的不适感。仪器同时输出两侧脑组织的血容量和氧含量曲线,可以实现对病人的双侧脑组织血、氧变化参数进行长时间实时、连续的监测。最后利用生物模型实验验证了仪器的有效性。The main purpose of this paper is to describe the design and development of the near-infrared bloodoxygen monitor which is based on the theory of detecting the blood- oxygen parameters of tissue by near- infrared, and the monitor can detect the blood-oxygen parameters of two sides of the local brain tissue. The monitor uses two wavelength ultra-high light LED as lamp-house, and two sensors detect the light scattered by two sides of the local brain tissue, which make the monitor achieve the function of dual detector. The appearance of the monitor＇s detector is designed to reduce effectively the noise brought by the background and alleviate the discomfort feelings of the patient. At the same time, this apparatus can monitor continuously the brain blood- oxygen parameters of the patients in real time, and output the curves of the blood-oxygen and oxygen concentration of two sides of brain tissue. At last, the biological model experiments and the tests in clinial setting validate the monitor.

关 键 词：近红外光 脑血氧 血容量 氧含量 

分 类 号：R318.6[医药卫生—生物医学工程]