N-(7-氟-3-氧-3,4-二氢-2H-苯并[b][1,4]噁嗪-6-基-)-N',N'-二取代脲类化合物的合成及除草活性  

Synthesis and Herbicidal Activity of N-(7-Fluoro-2,4-disubstitu-ted-3-oxo-3,4-dihydro-2H-benzo[b]oxazin-6-yl)-N',N'-disubstituted Urea Compounds

作　　者：李宏伟[1] 任叶果[2] 陈正旺[3] 闵忠诚[1] 胡礼[2] 黄明智[2] 

机构地区：[1]华中师范大学化学学院,湖北武汉430079 [2]湖南化工研究院国家农药创制工程技术研究中心,湖南长沙410007 [3]湖南师范大学化学化工学院,湖南长沙410081

出　　处：《精细化工中间体》2007年第6期22-25,共4页Fine Chemical Intermediates

基　　金：国家自然科学基金资助项目(20575019);"十一五"国家科技支撑计划资助项目(2006BAE01A01-4)

摘　　要：设计并合成了9个N-(7-氟-3-氧-3,4-二氢-2H-苯并[b][1,4]噁嗪-6-基-)-N',N'-二取代脲类化合物,其化学结构经IR、1HNMR、LC/MS确证。初步生物活性测定结果表明,部分化合物具有一定的除草活性,当茎叶处理使用剂量为75g a.i./hm2时,化合物4e和4h对双子叶杂草刺苋的抑制率达70%以上。Urea compounds are one of the hot topic in the herbicide research, Nine N-（7-fluoro-2,4-disubstituted-3- oxo-3,4-dihydro-2H-benzo [b] [ 1,4]oxazin-6-yl）-N＇,N＇- disubstituted urea compounds were designed and synthesized. Their structures were confirmed by IR, ^1H NMR and LC/MS spectra.The primary bioassay results showed that some title compounds had some herbicidal activities, for example, compound 4e and 4h exhibited more than 70% herbicidal activity against, Amaranthus spinosus at the rate of 75 g a.i./hm^2.

关 键 词：除草剂 苯并[b][1 4]噁嗪 乙酰胺 生物活性 

分 类 号：S482.4[农业科学—农药学]