常压羧化法制备2,6-二羟基苯甲酸  

Preparation of 2,6-Dihydroxybenzoic Acid by Carboxylation under Atmospheric Pressure

作　　者：张曼玲[1] 李春萍[1] 

机构地区：[1]内蒙古工业大学化工学院,呼和浩特010051

出　　处：《天然气化工—C1化学与化工》2007年第6期46-49,共4页Natural Gas Chemical Industry

摘　　要：研究了间苯二酚常压羧化法制备2,6-二羟基苯甲酸。分析了Kolbe-Schmitt羧化反应机理,选择了该反应的适宜溶剂。通过正交试验确定了反应的最佳参数。在优化的反应参数(间苯二酚/碳酸钾摩尔比1∶0.5,反应温度155～160℃,反应时间6～7h,溶剂为二甲基乙酰胺)下,2,6-二羟基苯甲酸收率达29.38%。2,6-Dihydroxybenzoic acid was prepared by carboxylation of resorcinol in solvent under under atmospheric pressure was studied. The mechanism of Kolbe-Schmitt carboxylation was analyzed and the sutable solvent for the carboxylation reaction was selected. The optimum process parameters were determined by orthogonal test. Under the optimized parameters, i.e. , resorcinol to potassium carbonate molar ratio of 1： 0. 5, reaction temperature of 155℃-160℃ , reaction time of 6 hours-7 hours, and dimethyl acetamide as solvent, the yield of 2,6-dihydroxybenzoic acid was up to 29.38% .

关 键 词：Kolbe-Schmitt反应 工艺参数 2 6-二羟基苯甲酸 制备 间苯二酚 二氧化碳 溶剂羧化 

分 类 号：TQ21[化学工程—有机化工]