陕西省定边县地方性氟中毒流行病学研究  

An Epidemiological Study on Endemic Fluorosis in Dingbian County

作　　者：白广禄[1] 陈宝群[1] 刘晓莉[1] 李俊岭[1] 王亚平[1] 范中学[1] 马长安[1] 张福金[1] 邓建霞[1] 郑来义[1] 华基礼[1] 武红英[1] 

机构地区：[1]陕西省地方病防治研究所,西安市710003

出　　处：《地方病通报》1997年第3期25-28,共4页Endemic Diseases Bulletin

基　　金：陕西省地方病防治办公室资助

摘　　要：作者对陕西省定边县地方性氟中毒进行了流行病学调查。结果表明，平原区氟斑牙患病率达88．19％。临床症状和体征的检出率为2O．84％，女性高于男性。病区83．66％的水源氟含量超过1．0mg／L，氟斑牙患病率和症状、体征的检出率与水氟含量及年龄增长相一致，尿氟与水氟呈正相关，粮食和空气不是主要摄氟介质。氟骨症患者血清碱性磷酸酶活性增高，血清钙含量降低，磷含量升高。地下水氟含量与地貌等因素有关。The endemic fluorosis was investigated in Dingbian county Shaanxi province. The results showthat prevalence rate of dental fluorosis is 88. 19 %, detective rate of clinical symptoms and signs is 20. 84% inplain. The detective rate of female with clinical symptoms and signs is higher than that of male. 83. 66 % ofwater sources in the endemic areas contain over 1. 0 mg/l fluoride. Prevalence rate of dental fluorosis and detective rate of clinical symptoms and signs correspond to fluoride level in drinking water and age. The urinefluoride has a positive relation to water fluoride. The air and food are not main sources of fluoride. AKP ofpatients with skeletal fluorosls is high. The serum Ca2 + content is low . PO4+ is high. The fluoride level ingroundwater relates to geomorphic conditions and other factors.

关 键 词：氟中毒 地方性氟中毒 流行病学 综合治理 

分 类 号：R599.01[医药卫生—内科学]