老年男性人群吸烟与血脂紊乱的关系研究  

The relationship between smoking and dyslipidoses in elderly male populations

作　　者：焦桂萍[1] 任雁京[1] 丁毅[1] 王秀荣[1] 高秀蓉[1] 谭新杰[1] 袁志柳[1] 

机构地区：[1]贵州省人民医院干部医疗科,贵阳550002

出　　处：《贵州医药》2007年第12期1062-1065,共4页Guizhou Medical Journal

基　　金：贵州省优秀科技教育人才省长专项基金项目(2005-25)

摘　　要：目的探讨吸烟对老年男性人群血脂紊乱的影响,为临床干预和健康教育提供资料。方法选取2004年1月至2006年12月在我科常规体检的贵州老年男性人群2160人,对其进行问卷调查、体格检查和血脂检查,包括年龄、吸烟史、饮酒史、体重指数、血压等情况。采用SPSS10.0统计软件对吸烟与总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(ApoB)和脂蛋白a[Lp(a)]的关系进行分析。结果吸烟者的TG水平明显高于不吸烟者和已戒烟者,而HDL-C水平却明显低于不吸烟者和已戒烟者(P<0.001)。吸烟者和已戒烟者的TG、TC及HDL-C水平异常与不吸烟者相比更常见。与轻度吸烟者相比,极重度吸烟者TG和ApoB异常更常见,TG和LDL-C异常在中重度吸烟者中更常见,HDL-C和Lp(a)异常却在轻度吸烟者中更常见。在将吸烟与其它影响血脂的因素(如饮酒、体重指数、年龄)进行比较后发现,吸烟对血脂紊乱的影响最大(β=0.219),当对这些影响因素进行校正分析后发现吸烟是血脂紊乱的一个独立危险因素(P=0.032)。结论吸烟对老年男性人群血脂紊乱具有重要的影响,积极戒烟和控制吸烟量将有助于维护老年男性人群的健康和减少相应的医疗费用。Objective To investigate the relationship between smoking and dyslipidoses in elderly males and provide information for clinic intervention and health education. Methodss 2160 elderly males were enrolled in this study from Jan 2004 to Dec 2006. The evaluation of the study population included a questionnaire a physical examination and lahoratory analysis of blood samples. The age, smoking history, alcohol intake, weight index and blood pressure were collected. The relationship between smoking and triglycerides （TG）, total cholesterol high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apoprotein B, lipoprotein （a） were analyzed by SPSS 10. 0 software. Results Levels of TG in current smokers were shown to be significantly higher and levels of high-density lipoprotein cholesterol （HDL-C） lower than for those who had never smoked or had stopped smoking （P〈0. 001）. Levels of TG total cholesterol （TC） and HDL-C in current smokers and those who had stopped smoking were more frequently abnonual than in those who had never smoked. In addition, levels of TG and apoprotein B were more frequently abnonual in very heavy smokers compared with light smokers, TG and low-density lipoprotein cholesterol levels were more frequently abnonual in medium and heavy smokers. HDL-C and Lp（a） levels were more frequently abnormal in light smokers. When comparing other factors that influence blood lipids such as alcohol intake, body mass index and age, smoking had the greatest influence （β=0. 219） and it was an independent risk factor for dyslipidoses （P=0. 032）. Conclusion Smoking has an important influence on elderly males and stop smoking and control of srnoking amount could protect the health of elderly males.

关 键 词：吸烟 血脂紊乱 老年 男性 

分 类 号：R592[医药卫生—老年医学] R589.2[医药卫生—内科学]