高效毛细管电泳技术测定肌苷口服液的含量  

Determination of Inosine in Oral Tonic by High Performance Capillary Electrophoresis

作　　者：杨迎迎[1,2] 孙发山 王磊[1,2] 张玉奎[1,2] 

机构地区：[1]大连医科大学 [2]中国科学院大连化学物理研究所

出　　处：《色谱》1997年第1期60-61,共2页Chinese Journal of Chromatography

摘　　要：介绍了应用高效毛细管电泳技术测定肌苷口服液含量的方法。实验是将肌苷口服液直接进样，以硼酸－硼酸盐为缓冲溶液。实验的回收率为９５．０％～９９．８％，相关系数０．９９８５，精密度的变异系数小于５％。方法简便、快速、准确。This paper describes a high performance capillary electrophoresis method for the assay of inosine in oral tonic. The method employed a boric acid borate buffer solution with SDS and UV detection at 254nm. The capillary was 47cm×75μm i.d.. Calibration curve shows good linearity. The recovery of inosine ranged from 95.0% 99.8% with a coefficient of variation (CV) of 2.4% (n=4). This method is simple, rapid and reliable.

关 键 词：高效毛细管电泳 肌苷 肌苷口服液 

分 类 号：R977[医药卫生—药品] O657.8[医药卫生—药学]