110例酒依赖患者的常见血清酶、血脂水平分析  

ANALYSIS OF COMMON SERUM ENZYME AND BLOOD LIPID IN 110 ALCOHOL-DEPENDENT PATIENTS

作　　者：刘光美[1] 雷燕[2] 徐成惠[1] 

机构地区：[1]攀枝花市第三人民医院,攀枝花617061 [2]重庆医科大学,重庆400016

出　　处：《中国药物依赖性杂志》2007年第6期448-450,共3页Chinese Journal of Drug Dependence

摘　　要：目的:了解酒依赖患者的常见血清酶、血脂水平。方法:应用0LYMPUS AU-400全自动生化分析仪,对符合CCMD-3诊断标准酒依赖患者110例,分别测定其常见血清酶和血脂,并与90例健康者组成的对照组进行比较。结果:酒依赖组的血清丙氨酸氨基转移酶(ALT)、天门冬氨基转移酶(AST)、碱性磷酸酶(ALP)、谷氨酰转肽酶(GGT)、肌酸激酶(CK)及乳酸脱氢酶(LDH)等血清酶类指标显著高于正常对照组(P<0.01)。酒依赖组的血清三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-c)、载脂蛋白B(ApoB)显著高于正常对照组(P<0.01);其高密度脂蛋白胆固醇(HDL-c)、载脂蛋白A1(ApoA1)显著低于正常对照组(P<0.01);而总胆固醇(TC)两组之间差异无显著性(P>0.05)。结论:酒依赖患者的常见血清酶类指标及血脂有不同程度的改变。应大力宣传饮酒成瘾的危害和酒精依赖的防治知识,对酒依赖的患者应早诊断早治疗。Objective：To investigate the level of common serum enzyme and blood lipid of alcohol-dependent patients. Methods：The level of common serum enzyme and blood lipid of 110 alcohol-dependent patients diagnosed with CCMD-3 diagnostic criteria was measured by OLYMPUS AU-400 automatic biochemical analyzer, the result of which was compared with that of 90 health adults. Results：The level of serum enzyme such as ALT, AST, ALP, GGT, CK, LDH of alcohol-dependent patient group was significantly higher than that of the control group（P〈0.01）,and the level of serum TG, LDL-c, ApoB was significantly higher too（P〈0.01）, while the level of serum HDL-c, ApoA1was significantly lower（P〈0.01）, but the level of TC had no significant difference in the two groups（P〉0.05）. Conclusion：Different degrees of changes are observed in the level of common serum enzyme and blood lipid of alcohol-dependent patients. It should strongly publicize the harm of alcohol addiction and the knowledge of prevention and cure of alcohol-dependence. Alcohol-dependent patients should be early diagnosed and cured.

关 键 词：酒依赖 血清酶 血脂 

分 类 号：R544.1[医药卫生—心血管疾病]