红花注射液致不良反应文献分析  

Literature Analysis of Honghua Injection-induced Adverse Reaction Cases Reported

作　　者：郑高峰[1] 张玉红[1] 林艺娟[1] 

机构地区：[1]四川省简阳市人民医院药剂科,四川简阳641400

出　　处：《中国药业》2008年第1期40-41,共2页China Pharmaceuticals

摘　　要：目的探讨红花注射液致不良反应(ADR)的临床特点。方法检索《中国医院数字图书馆》全文数据库中2000—2006年国内医药学期刊有关红花注射液致ADR的报道,并进行统计、分析。结果有关红花注射液致ADR的报道共涉及患者39例,其中男20例,女19例,年龄50岁以上发生率较高;ADR主要为过敏反应,且过敏性休克发生率较高;ADR在30min内发生者22例(56.41%),首次用药发生者有30例(76.92%),提示红花注射液致ADR以首用即发型和速发型为主。结论临床应重视红花注射液的ADR,合理用药。Objective To discuss the regulation of adverse drug reaction （ADR） caused by Honghua Injection. Methods Honghua Injection- induced ADRs cases reported in the internal pharmaceutical journals retrieved from 2000 to 2006 were collected and analyzed statistically from CHKD. Results 39 cases of Honghua Injection- induced ADRs （male 20, female 19） were collected. ADRs often occurred among those people over age 50. Its chief clinical manifestation was allergic reaction with the high frequency of hypersensitive shock, The onset of ADRs in 22 cases （56.41%） occurred within 30min after injection, 30 cases （76.92%） occurred in their fL,＇st time of medication, which suggested that the major ADRs types were the firstusing immediate types and the speedy outbreak types. Conclusion More attention should be paid to Honghua Injection- induced ADRs and the rational drug use can be ensured.

关 键 词：红花注射液 不良反应 过敏反应 文献分析 

分 类 号：R288[医药卫生—中药学]