骨重建数值仿真中的控制方程  

Review of bone remodeling criteria in numerical simulation

作　　者：程亮[1] 王冬梅[1] 王成焘[1] 

机构地区：[1]上海交通大学机械与动力工程学院,上海200240

出　　处：《医用生物力学》2007年第4期417-422,共6页Journal of Medical Biomechanics

摘　　要：人体骨组织有着复杂的结构和生理机制,骨重建理论经历了定性分析、定量计算和计算机定量数值模拟三个阶段。目前,存在力学模型和现象模型两类成熟的骨重建模型,力学模型的共性就是表观密度随一定的力学刺激而变化,现象模型由基本多细胞单元的损伤状态和孔隙度变化来决定。大多数股骨重建仿真模型仍然将骨量的分布看作是各向同性的,这就不能完全反映骨组织微构造的本构关系。本文是对骨重建仿真模型的控制方程进行综述。Bone tissue has complex structure and biological system. The history of bone remodeling theory experiences three main periods： qualitative analysis, quantitative analysis and fix quantify value simulation by computer. Nowadays, there are two common bone remodeling models based on mechanical approach and phenomenological approach respectively. The mechanical model has the same basis that the apparent density is designed as a direct response to a certain mechanical stimulus. Otherwise, the phenomenological model is largely dependent on Basic Multicellular Units （BMU） damage and porosity change. Most of remodeling methods are isotropic, which does not denote constitutive relation of bone microstructure. This paper has reviewed bone remodeling criteria in Numerical Simulation.

关 键 词：骨重建 控制方程 弹性适应理论 有限元方法 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]