肌钙蛋白Ⅰ与肌红蛋白定时定量监测在急性心肌梗死诊疗过程中的临床观察  

Clinical Observation of Quantitative Analysis of Cardiac Troponin I and Myoglobin in Patients with Acute Myocardial Infraction

作　　者：胡章学[1] 张涛[1] 王婷[1] 孟红[1] 

机构地区：[1]安康市中心医院核医学科,陕西安康725000

出　　处：《标记免疫分析与临床》2007年第4期210-211,220,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：根据心肌肌钙蛋白Ⅰ(cTnI)与肌红蛋白(Mb)在急性心肌梗死(AMI)发生后的定时定量分析结果比较,为AMI的早期诊断提供更灵敏、更准确的监测指标。本文采集95例AMI患者于胸痛发作0～4h、8h、12h、24h、48h、3天、5天和7天的血清,以及对照组38名的空腹血清同步进行cTnI与Mb的动态检测和比较,结果发现,AMI患者的早期0～4h Mb的灵敏度明显高于cTnI;而8h后cTnI的灵敏度和准确度明显高于Mb。To explore the clinical value of cardiac troponinⅠ （cTnⅠ） and myoglobine （Mb） in the early diagnosis of acute myocardial infraction （AMI）, the serum cTn I and Mb were detected in 95 AMI patients at various time phase including 0-4 h, 8 h, 12 h, 24 h, 48 h, 3 days, 5 days and 7 days after they got breastach, and 38 healthy controls. The results showed that the sensitivity of Mb in the diagnosis of AMI was higher than that of cTnⅠ when the AMI occurred in 0-4 hours. However, the sensitivity and accuracy of cTnⅠ in the diagnosis of .AMI were higher than that of Mb in 8 hours later.

关 键 词：急性心肌梗死 心肌肌钙蛋白Ⅰ 肌红蛋白 

分 类 号：R542.22[医药卫生—心血管疾病]