磁场对铁卟啉仿生催化性能的影响  

Influence of Magnetic Field on the Biocatalytic Properties of Ironporphyrin

作　　者：郭灿城[1] 郝旭东[1] 张晓兵[1] 梁本熹[1] 陈新斌[1] 

机构地区：[1]湖南大学化学化工学院,长沙410082

出　　处：《高等学校化学学报》1997年第6期906-907,共2页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金;机械部优秀人才基金

摘　　要：Monometalloporphyrin and p-oxo-bismetalloporphyrin compounds of metal iron,manganese and cobalt were synthesized, and used as the model compounds of cytochrome P-450 monooxygenase in catalytic oxidation of cyclohexane with iodosobenzene. The influence of the addition of magnetic field on the catalytic properties of these metalloporphyrins was in-spected. The studies reveal that the influence of the addition of magnetic field on the catalyt-ic behavior of other metalloporphyrins does not go beyond 37% except monoironporphyrin.But the addition of magnetic field makes the reaction yield of cyclohexane oxidation catalyzed by monoironporphyrin be increased to 53%, and makes the rate of reaction be twice as much. This fact means that the catalytic processes of cytochrome P-450 monooxygenase in human bodies may be bound up with earth magnetic field closely. This discovery has singular meaning to unlock the mystery of biosphere consisting of human and earth.Monometalloporphyrin and p-oxo-bismetalloporphyrin compounds of metal iron,manganese and cobalt were synthesized, and used as the model compounds of cytochrome P-450 monooxygenase in catalytic oxidation of cyclohexane with iodosobenzene. The influence of the addition of magnetic field on the catalytic properties of these metalloporphyrins was in-spected. The studies reveal that the influence of the addition of magnetic field on the catalyt-ic behavior of other metalloporphyrins does not go beyond 37% except monoironporphyrin.But the addition of magnetic field makes the reaction yield of cyclohexane oxidation catalyzed by monoironporphyrin be increased to 53%, and makes the rate of reaction be twice as much. This fact means that the catalytic processes of cytochrome P-450 monooxygenase in human bodies may be bound up with earth magnetic field closely. This discovery has singular meaning to unlock the mystery of biosphere consisting of human and earth.

关 键 词：卟啉 金属卟啉 铁卟啉 酶 仿生 磁场 催化氧化 

分 类 号：O627.81[理学—有机化学]