2-(N-苯基甲酰胺基)苯并异噻唑啉-3-酮类化合物的合成及生物活性测试  

Synthesis and Bioactivity Test of 2-(N-phenylformamide)-3-oxo-phenylbenzo Isothiazoles

作　　者：贺永宁[1] 袁文[1] 王向辉[1] 杨建新[1] 林强[1] 

机构地区：[1]海南大学教育部热带生物资源重点实验室,海南海口570228

出　　处：《海南大学学报（自然科学版）》2007年第4期345-348,共4页Natural Science Journal of Hainan University

基　　金：海南省自然科学基金资助项目(20503)

摘　　要：以苯并异噻唑啉-3-酮和取代异氰酸苯酯类化合物为原料,合成了7种新的2-(N-苯基甲酰胺基)苯并异噻唑啉-3-酮类化合物,目标化合物的结构经1HNMR,MS,IR确证;并对新合成的化合物进行了水生菌杀菌活性测试.Seven new 2-（N- phenylformamide）-3 （2H）-oxo-phenylbenzo isothiazoles had been synthesized by the reaction of substituted phenyl isocyanate with benzo isothiazol-3 （2H）-one and substituted phenylisocyanate. Their structures had been confirmed by 1HNMR, IR spectra, and MS spectra. All compounds had been tested by fungicidal activity.

关 键 词：苯并异噻唑啉-3-酮 合成 生物活性 

分 类 号：O625.4[理学—有机化学]