下鼻甲黏膜切开术治疗变应性鼻炎  

Inferior turbinate mucosa section for allergic rhinitis

作　　者：徐福杰[1] 林志娟[2] 秦浩[3] 

机构地区：[1]昌邑市人民医院耳鼻咽喉科,山东昌邑261300 [2]潍坊医学院分子免疫学研究所,山东潍坊261042 [3]潍坊医学院预防医学系,山东潍坊261042

出　　处：《山东大学耳鼻喉眼学报》2007年第6期540-541,544,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的探讨常年变应性鼻炎及并发支气管哮喘患者行下鼻甲黏膜切开术的疗效。方法对72例常年变应性鼻炎患者施行下鼻甲黏膜切开术,采用等级资料的秩和检验分析术后3个月及1年的疗效,采用配对资料的t检验分析手术前后1年支气管哮喘的发作时间。结果随访3个月显效66例,有效5例,无效1例;随访1年显效28例,有效35例,无效9例;差异有统计学意义(Mann-Whitneyu=1 219,P<0.01)。12例合并有支气管哮喘者1年发作哮喘的总时间术后为(71.66±63.26)h,术前为(89.25±75.65)h,差异有统计学意义(t=2.96,P=0.01)。结论下鼻甲黏膜切开术治疗常年变应性鼻炎在短期内有一定疗效,随时间延长效果减弱,对合并支气管哮喘者有一定疗效。Objective To explore the treatment method of perennial allergic rhinitis. Methods 72 patients with perennial allergic rhinitis had inferior turbinate mucosa section performed. The rank-sum test of ranked data was used to analyze the curative effect at 3 months and 1 year after the operations, the t-test of pairing data was used to analyze the stroke time of bronchial asthma 1 year before and after the operations. Results Followed up for 3 months, 66 patients had excellent effect, 5 had effect and 1 had no effect. Followed up for 1 year,28 patients had excellent effect, 35 had ef- fect and 9 had no effect. The difference was statistically significant（ u = 1 219, P 〈 0.01）. In 12 patients combined with bronchial asthma, the total stroke time was 71.66 ±63.26 h after operations and 89.25 ±75.65 h before operations, there was statistical significance （ t = 2.957, P = 0.013）. Conclusions Inferior turbinate mucosa section is invariably valid for perennial allergic rhinitis for a short time and the effect will be weakened with time. It is valid for patients with bronchial asthma.

关 键 词：鼻炎 变应性 常年性 哮喘 下鼻甲 外科手术 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]