子宫内膜异位症合并不育患者体外受精-胚胎移植治疗结局分析  

The Retrospective Analysis on the Outcome of IVF-ET for Patients with Infertility by Endometriosis

作　　者：黄筱金[1] 韩艳[1] 柳鸣[1] 黄建贞[1] 易红霞[1] 

机构地区：[1]南昌大学第一附属医院辅助生殖科,南昌330006

出　　处：《实用临床医学（江西）》2007年第12期74-77,共4页Practical Clinical Medicine

摘　　要：目的:观察体外受精-胚胎移植(IVF-ET)治疗周期子宫内膜异位症对IVF-ET治疗结果的影响。方法:22例23个周期子宫内膜异位症合并不育症患者(A组)以及同期随机抽取36例36个周期输卵管性不育患者(B组)进行对比,从使用Gn量、使用Gn天数、获卵数、卵裂数、受精数以及临床妊娠率等方面进行比较分析。结果:Gn用量、Gn用药天数有统计学意义(P<0.05),获卵数、受精数、卵裂数、种植率、临床妊娠率比较差异无显著性(P>0.05)。结论:子宫内膜异位症患者卵巢储备能力下降,促性腺激素用量增加,但卵母细胞受精能力,胚胎种植率和临床妊娠率与输卵管性因素不育结果相似。Objective：Tto investigate and analyze the effect of endometriosis on in vitro fertilization and embryo transfer according to the comparison between the infertility patients with endometriosis or tubal-factor. Methods.Twenty-two patients with endometriosis （group A） underwent 23 cycles of IVF-ET. The matched control group with tubal-factor infertility （group B） consisted of 36 cycles in 36 patients. These groups were analyzed regarding stimulation, fertilization, cleavage, implantation, and pregnancy outcome. Results： The requirement of gonadotropin and the days of controlled ovarian hyperstimulation （COH） higher （P〈0.05）, but the cleavage, fertilization, implantation, and pregnancy rate did not differ between the two groups. Conclusion. Our results show that women with endometriosis presented a poor ovarian response to controlled ovarian hyperstimulation, but the ability for the oocyte to be fertilized, the implantation and pregnancy rate were similar to the tubal-factor infertility.

关 键 词：子宫内膜异位症 不育 体外受精-胚胎移檀 

分 类 号：R711.6[医药卫生—妇产科学]