成人呼吸系统疾病中呼吸道合胞病毒的监测  

The monitor of respiratory syncytial virus in adult respiratory disease

作　　者：刘泽英[1] 刘双[1] 梁瑛[1] 何善娴[2] 臧宝霞[3] 李蔚然[4] 

机构地区：[1]首都医科大学附属北京安贞医院呼吸内科,北京100029 [2]首都医科大学附属北京安贞医院体检中心,北京100029 [3]北京市心肺血管疾病研究所药理研究室 [4]首都医科大学附属北京安贞医院体外循环,北京100029

出　　处：《心肺血管病杂志》2008年第1期31-33,共3页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:了解呼吸道合胞病毒(RSV)在成人呼吸系统疾病中的发病情况。方法:对呼吸科住院患者253例及同期健康体检者200例静脉血清用酶联免疫法(ELISA)测定RSV抗体IgM。结果:对照组阳性12例,阳性率6%;患者组阳性37例,阳性率14.6%,其中慢性阻塞性肺病(COPD)、肺炎与对照组比较差异有显著性(P<0.05);急性支气管炎、肺间质纤维化、结核性胸膜炎与对照组比较差异有显著性(P<0.01)。本组患者秋冬季发病较多,阳性率19.5%,春夏季阳性率9.6%,二者相比差异有显著性(P<0.05)。结论:RSV是成人呼吸道感染的重要病原,可引起下呼吸道炎症(如COPD、肺炎、急性支气管炎、肺间质疾病等)的发生和反复发作,应引起重视。Objective：To understand the incidence of respiratory syncytial virus （RSV）in adult respiratory disease. Method： Venous serum RSV-IgM in 253 inpatients with respiratory disease and 200 healthy people was measured by enzyme-linked immuosorbent assay （ELISA）. Resnit ：37 cases were positive in inpatients and the positive rate was 14.6%, while the positive rate of healthy people was 6.0% . Compared with healthy people, the positive rate of COPD and pneumonia showed a significant difference （ P 〈 0.05）, and the positive rate of acute bronchitis, lung institial fibrosis and tuberculous pleuritis also showed a obvious difference （ P 〈 0.01 ）. The incidence rate in autumn and winter was higher than that in summer and spring, the former accounts for 19.5%, and the latter did 9.6% （P 〈 0.05）. Conclusion： RSV is common in adult respiratory infection, it is important etiology, which should be emphasized.

关 键 词：呼吸系统疾病 呼吸道合胞病毒 

分 类 号：R56[医药卫生—呼吸系统]