基于蒙特卡罗的IMRT模拟研究  

The simulation of IMRT based on Monte carlo method

作　　者：张俊广[1] 张春光[1] 梁少华[1] 陈剑艺[1] 曾达夫[1] 潘国雄[1] 

机构地区：[1]华南肿瘤学国家重点实验室

出　　处：《中国医学装备》2008年第1期10-12,共3页China Medical Equipment

摘　　要：目的:通过MCNP程序建立加速器治疗头模型,人体模型,模拟粒子从靶点到人体内的能量分布,得到肿瘤靶区剂量分布情况,观察其是否达到IMRT的要求。方法:基于MCNP程序建立模型,模拟人体头部截面近似为圆形,由一层骨骼组织包围着软组织,肿瘤理想化为一圆柱状结构。射线以肿瘤为中心从不同角度入射,由MeNP程序计算出能量分布情况。结果:模拟结果显示,靶区剂量分布很好地符合了靶区的三维形状。体现出IMRT靶区剂量均匀,精确的治疗效果。通过改变能量和分段时间的注入,提高肿瘤处的致死剂量和减少正常组织受照剂量,可以优化治疗方案。结论:MCNP程序对计算光子,电子相关的物理输运问题有强大的作用。Methods： In this article, we build the MCNP model of the linac head and the body, Simulate the energy deposition from the linac head to the tumor in the body, which reflect the dose distribution. The head model was constructed by parenchyma covered by round skull. The tumor was identified to a column frame. The irradiation take tumor as the center, irradiate from different angle. Then work out the energy distribution by MCNP. Result： The result shows the dose distribution in the tumor fit the tumor figure very well. With the different energy and time injection, we can get the optimal Rx. Conclusions： Procedure of MCNP has powerful function for compute the particle transport problems that relate to the photon and electron.

关 键 词：IMRT治疗 MONTE carlo MCNP 人体模型 

分 类 号：TH774[机械工程—仪器科学与技术]