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作 者:赵亚平[1]
机构地区:[1]北京儿童医院,100045
出 处:《新生儿科杂志》1997年第4期159-160,共2页The Journal of Neonatology
摘 要:新生儿高钠血症9例,原发病为腹泻、肺炎、败血症化脑、延迟喂养及鼻眼净中毒。病史均<2天。高钠病因:单纯水缺乏,丢失低渗液,输含钠液过多。症状及体征除4例腹泻患儿伴中重度脱水外,其余均不明显。神经系统症状有烦躁和嗜睡,肌张力增高5例。血钠在159~177mmol/L,血氯110~145mmol/L,血钾增高7例6.4~9.5mmol/L。治疗中除中重庆脱水先予扩容外,全部用1/3~1/10张液缓慢48小时内输入。血钠在24~72小时内恢复正常。随访7例,1例化脑有智力障碍,其余智力正常。9 cases of neoratal hyperatremia were studied. The underlying diseases were diarrha, pneumonia, septicemia, bacterial meningitis, feeding delayed and toxicity of Naphazoline, The courses before admitted were less thar 2 days in all cases. The main causes of hyperna tremia were evaporative losses of water. lsosses of excessive hypotonic fluid and excessiv infsi on of sodium. 4 cases with diarrhea had moderate of sever dehydration. S cases had the signs of nervous system including irrittion drowsy, hypermyotorua, no other syptoms or signs was found serum sodium concen-toation was oetweer 159-177 mmol/L. Chloride, 110 -145 mmol/L. Hyperkelemia in 7 cases 6. 4-9. 5 mmol/L Bun elevated in 7 cases, hyper glycemia in 3 cases. hypocalomia in 4 cases. The cases with severe dehdration were treated by rapidhy exponding the blood volum at first. in other cases 1/3-1/10 osmclar fluid was replaled slowhy during the 48 hours Serum sodium concentration returnedto normal. during 24) 72 hours. 7 cases were fouowed up. We did't find any mental defect, except one case with bacterial meningitis The character and treatment of neonatal hypernatremia were dis cussed, Sever hypernatremia should be treated by peritoneal dialysis.
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