围产新生儿气漏危险因素分析  

Study of the risk factors of perinatal pulmonary air leak syndrome

作　　者：于文红[1] 刘瑞霞[1] 郑军[1] 

机构地区：[1]天津医科大学第二医院新生儿科,300211

出　　处：《中国新生儿科杂志》2008年第1期20-22,共3页Chinese Journal of Neonatology

摘　　要：目的探讨围产新生儿气漏发病的危险因素。方法2000年11月至2005年9月新生儿气漏40例,采用回顾性病例对照研究方法,随机选择对照病例80例,应用SPSS软件进行分析。结果新生儿气漏足月儿较早产儿发病高(χ2=5.72,P<0.05);单因素及多元回归分析无产兆剖宫产、肺部疾病、nCPAP及机械通气均为危险因素,特别指出当应用nCPAP吸氧浓度较初始吸氧浓度增加50%以上提示气漏发病可能。结论足月儿避免非病理因素的无产兆剖宫产可降低气漏发病危险。应用nCPAP吸氧浓度较初始吸氧浓度增加50%以上应高度警惕气漏可能性。Objective To study the risk factors of air leak syndrome of newborns in the perinatal period. Methods Forty cases of air leak syndrome of newborn between November, 2000 and September, 2005 were analyzed retrospectively. Eighty control cases born during the same period were randomly selected with comparable birth weight and gestational age. The statistical analysis was done by using SPSS software, odds ratio and 95% confidence interval were used to identify possible risk factors. Results That the incidence of air leak syndrome was higher in full term newborns than preterm newborns （χ^2 = 5.72, P 〈 0. 05）. Monofactor and logistic regression analysis indicated that the risk factors of air leak syndrome during perinatal period were prelobor caesarean section, lung diseases, continuous positive airway pressure and mechanical ventilation. Conclusions The risk of air leak syndrome can be lowered by avoiding caesarean section not in labor or without any indications in full term infants. It is also alarming for onset of air leak syndrome when the fraction of oxygen is increased to more than 50% of the initial value during nCPAP treatment.

关 键 词：危险因素 婴儿死亡率 临床方案 

分 类 号：R722.1[医药卫生—儿科]