基于高精度断层图片数据集的大鼠动脉血管重建  

Reconstruction of rat artery based on high resolution cross-section images data

作　　者：武力[1] 李安安[1] 谢添武[1] 刘谦[1] 

机构地区：[1]武汉光电国家实验室(筹)生物医学光子学研究部,430074

出　　处：《国际生物医学工程杂志》2007年第6期321-323,共3页International Journal of Biomedical Engineering

基　　金：国家863计划资助项目(2006AA02Z343)

摘　　要：目的基于微米级大鼠断层图片数据集,建立高精度的大鼠动脉血管的三维模型,为各种监测鼠血管组织形态变化的试验提供客观依据。方法采用一套高分辨率大鼠断层切片图像数据集,使用半自动交互方法对动脉血管进行分割,使用改进的移动立方体(marching cube,MC)算法,在一台IBM图形工作站上对80 GByte大小的血管图片数据集进行重建。结果建立了完整的高精度大鼠动脉血管的三维表面模型,能显示出0.4mm大小的微细血管。结论该大鼠动脉血管三维模型可以为观测试验鼠血管组织形态变化提供一个立体的空间比较标准。Objective To provide evidence of the changes in the modality of rat artery in observational experiments, an accurate 3D model of the rat artery was reconstructed using rat images data with micrometer-leveled resolution. Methods A set of data about 80 GByte from high resolution cross-section images of rat was obtained to segment the artery. A 3D model of the artery wass reconstructed with the advanced Marching Cub algorithm on an IBM Image Station. Results A complete high resolution 3D model of the rat artery with tiny blood vessel of 0.4 mm width visible was obtained. Conclusion The 3D model of the rat artery built could provide a new spatial comparing criterion for the experimenters to estimate the morphological changes of rat artery.

关 键 词：移动立方体算法 断层切片 三维重建 动脉血管 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]