立体定向多靶点手术治疗情感性精神障碍  

Stereotactic multi-taryet operation for patients with affective disorder

作　　者：王连仲 尹忠民 闻华 江晓莲 王磊 

机构地区：[1]解放军第四六三医院神经外科全军精神病外科治疗中心,沈阳110042

出　　处：《中华外科杂志》2007年第24期1676-1678,共3页Chinese Journal of Surgery

摘　　要：目的探讨螺旋 CT 引导下同期双侧多靶点于术治疗情感性精神障碍的疗效和安全性。方法采用螺旋 CT 定位,对182例情感性精神障碍患者,采用同期双侧多靶点射频热凝手术治疗。按全国精神外科协作组于1990年制定的评定方法进行疗效评定。结果 182例患者术后2周随访:显著改善86例,改善81例,无效15例,加重0例,有效率91.76%;166例术后随访6～54个月:恢复38例,显著改善59例,改善52例,无效17例,加重0例,有效率89.76%;术后除早期一过性并发症外,远期并发症发生率小于1%。结论螺旋 CT 引导同期双侧多靶点手术治疗情感性精神障碍疗效显著,安全性高。Objective To explore the efficacy and complication of bilateral multi-target radiofrequency lesion operation in patients with affective disorder. Methods One hundred and eighty-two eases with affective disorder were treated with unstaged bilateral multi-target radiofrequency thermocoagulation. The efficacy was evaluated with the method established in 1990 by the National Psychosurgery Cooperative Group. Results After 2 weeks of operation, 86 cases with remarkable improvements, 81 cases with improvements, 15 case with no improvements, no case with progression, total efficient ratio was 91.76%. With 6-54 montbes of follow-up to all of 166 cases, 38 cases with recovery, 59 cases with remarkable improvements, 52 cases with improvements, 17 cases with no improvements, no case with progression, total efficient ratio was 89. 76%. Except for early temporal complication of sterootactic operation, the long-term complication ratio was less than 1%. Conclusion CT-guided bilateral multi-target operation is prominent in treatment of affective disorder with high efficacy and safety.

关 键 词：精神外科手术 立体定位技术 射频毁损 

分 类 号：R651[医药卫生—外科学]