3,6-二甲基哒嗪的合成  

Synthesis of 3,6-dimethylpyridazine

作　　者：辛炳炜[1] 

机构地区：[1]德州学院化学系,山东德州253023

出　　处：《德州学院学报》2007年第6期37-38,44,共3页Journal of Dezhou University

基　　金：国家自然科学基金(20571063)

摘　　要：为填补国内市场空白,以乙酰乙酸乙酯、钠为原料;通过关环、脱氢等反应,高产率地合成了3,6-二甲基哒嗪.该方法步骤短,收率高,是合成3,6-二甲基哒嗪的一种简捷方法.In order to resolve the problem which 3,6--dimethylpyridazine can＇t be bought from domestic market, we prepare this compound by three steps from CH3COCH2COOCH2CH3 via cyclization with hydrazine hydrate and dehydrogenation reactions. The synthetic route is a excellent method to 3, 6--dimethylpyridazine. Its structure was characterized by^1 H NMR and MS--ESI.

关 键 词：3 6-二甲基哒嗪 4 5-二氢-3 6-二甲基哒嗪 2 5-已二酮 合成 

分 类 号：O621.258[理学—有机化学]