儿食健宝颗粒对幼龄厌食大鼠模型空肠段SP、VIP、SS表达影响的实验研究  

Regulatory Effect of Erbao Granules on SP、VIP、SS in Jejunum Rat Model of Anorexia

作　　者：刘淑娥 

机构地区：[1]河北省滦平县中医院,河北滦平068250

出　　处：《河北医学》2007年第12期1217-1219,共3页Hebei Medicine

摘　　要：目的:从胃肠激素水平探讨健脾中药儿食儿食健宝颗粒治疗小儿厌食症的作用机制。方法:用饮食不当法复制幼龄厌食症大鼠模型,通过观察肠内P物质(SP)、血管活性肠肽(VIP)、生长抑制素(SS)水平的变化,以及胃肠病理形态学改变,观察儿食健宝颗粒的作用。结果:儿食健宝颗粒可以改善厌食症大鼠SP、VIP、SS水平变化及胃肠粘膜病理形态。结论:儿食健宝颗粒可改善厌食症大鼠胃肠黏膜的病理形态学改变,并对SP、VIP、SS具有调节与平衡作用。Objective： To discuss the mechanism of Ershi granules （ ESG ） - the decoction of benefiting spleen transporting and transforming used in anorexia from the view of incretion of assimilation. Method：Juvenile rat model of anorexia was established by imitating the major cause of infantile anorexia through improper - diet. Through the obser ration of not only SubstanceP （ SP ） ; Intestinal Peptide （ VIP ） and Somatostatin （SS） inintestine, but also pathology morphological change can we observe thefunction of EBG. Result： EB- Gcan benefit bothSP, VIP, Ssand pathology morphologic of digestive membrane. Conclusion： EBG can benefitthe change of pathology morphologic of digestive membrane, as well benefit the regulation and balance of SP.VIP.SS.

关 键 词：厌食症 儿食健宝颗粒 P物质 血管活性肠肽 生长抑制素 

分 类 号：R285.5[医药卫生—中药学]