加强血小板功能试验在抗血小板药物治疗监测中的应用  

Strengthen the application of platelet function tests in monitoring antiplatelet drug treatment

作　　者：王建中[1] 

机构地区：[1]北京大学第一医院检验科,100034

出　　处：《中华检验医学杂志》2008年第1期9-12,共4页Chinese Journal of Laboratory Medicine

摘　　要：可用于抗血小板药物预防或治疗血栓性疾病监测的血小板功能试验有多种，可根据不同药物选择监测试验，包括阿司匹林、氯吡格雷和血小板膜糖蛋白（GPⅡb／Ⅲa）拮抗剂的监测。不同血小板功能试验确认的药物抵抗性存在差异，与临床不良事件的相关性有待确认。Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases. These monitoring tests may be chosen based on different antiplatelet drugs which inelude aspirin, elopidogrel and GP Ⅲ b/Ⅲ a antagonist. There is difference of the drug resistance which is validated by different platelet function tests, and the relation with clinical adverse events should be farther clarified.

关 键 词：血小板功能试验 血小板聚集抑制剂 药物监测 阿司匹林 噻氯匹定 血小板膜糖蛋白类 

分 类 号：R686[医药卫生—骨科学]