妥布霉素效价的浊度法测定  

Determination of Tobramycin by Turbidimetric Method

作　　者：湛文青[1] 彭洁[1] 魏嘉陵[1] 蒋忠军[1] 

机构地区：[1]广东省药品检验所,广东广州510180

出　　处：《中国医药工业杂志》2008年第1期45-47,共3页Chinese Journal of Pharmaceuticals

摘　　要：建立了浊度法测定妥布霉素的效价。选用金黄色葡萄球菌[CMCC(B)26003]为试验菌,妥布霉素在0.3～1.1μg/ml范围内,吸光度与其浓度的对数线性关系良好。平均回收率为100.3%,RSD为3.1%。A turbidimetric method was established for the determination of tobramycin. Staphylococcus aureus [CMCC （B） 260031 was used as the test bacteria. The logarithm of drug concentration and its absorbance had a good linearity in the concentration range of 0.3 - 1. μg/ml. The average recovery was 100.3% with RSD of 3.1%.

关 键 词：妥布霉素 浊度法 效价 测定 

分 类 号：TQ460.72[医药卫生—药物分析学] O657.32[化学工程—制药化工]