非淋菌性尿道炎患者衣原体、支原体检测与药敏分析  

Analysis of Detection and Susceptibility Results for Chlamydia and Mycoplasma Strains From Non-gonococcus Urethritis Patients

作　　者：段贞[1] 陈玮[1] 李浩[1] 蔡瑞芸[1] 

机构地区：[1]湖南省人民医院,湖南长沙410005

出　　处：《实用预防医学》2007年第6期1894-1896,共3页Practical Preventive Medicine

摘　　要：目的了解可疑非淋菌性尿道炎(NGU)患者泌尿生殖道分泌物衣原体、支原体感染及药敏情况。方法应用衣原体试剂盒(胶体金法)定性检测衣原体抗原,支原体培养及药敏选用支原体药敏试剂盒,并对10种抗生素对支原体的敏感性进行了分析。结果2034例可疑NGU患者检出各种病原体感染765例,阳性率37.6%,其中衣原体阳性者384例(18.9%),支原体阳性者324例(15.9%),混合感染者57例(2.8%)。381例支原体对10种抗生素的敏感率最高的是交沙霉素和强力霉素(89.76%、88.45%),其次为克拉霉素(69.55%),耐药率最高的是环丙沙星(93.44%),其次为红霉素(64.31%)和可乐必妥(56.96%)。结论诊治NGU患者感染,应进行衣原体、支原体检测和药敏试验,选择敏感有效的抗生素,控制NGU的传播和蔓延。Objective To investigate chlamydozoan and mycoplasma in urogenital tract infection and their susceptibilities to antibiotics in suspected non- gonococcus urethritis （NGU） patients. Methods Chlamydozoan antigen was qualitatively determined using colloidal gold technique. Mycoplasma culture and drug susceptibility were carried out with mycoplasma drug sensitivity kit, and the sensitivity of 10 kinds of antibiotics to mycoplasma was analyzed. Results Among the 2,034 patients suspected with NGU, 765 were positive with various pathogens, and the positive rate was 37.6%. The positive rates of chlamydozoan, mycoplasma and mixed both infection were 384, 324, and 57 respectively. Among the 381 mycoplasma infection cases, the sensitive antibiotics were josamycine （89.76 % ）, doxycycline （88.45 96 ）, and clarithromycine （69.55 96 ） ; however, mycoplasma was not sensitive to ciprofloxacin （93.44 96 ）, erythromycin （64.3196 ） and cravit （56.96 96 ）. Conclusions Diagnosis of NGU patient should be conducted along with the determination of chlamydozoan and mycoplasma and the drug sensitivity tests, and the sensitive and effective antibiotics play the important roles in curing and controlling nongonococcus urethritis.

关 键 词：非淋菌性尿道炎 衣原体 支原体 药敏试验 

分 类 号：R691.3[医药卫生—泌尿科学]