深低温冷冻与常温储骨对皮质骨生物力学特性影响的研究  

Study on the Cryopreservation and the Room Temperature's Effect to the Biomechanics Characteristics of the Cortical Bone

作　　者：杨克强[1] 李柱林[1] 张春林[2] 王臻[3] 胡蕴玉[3] 杨牧[1] 谷孝将[1] 谢小荣[1] 刘慧峰[1] 张鑫[1] 赵盛坤 李光新[4] 

机构地区：[1]中国人民解放军第255医院外二科,河北唐山063000 [2]河北北方学院附属第一医院骨科,河北张家口075000 [3]第四军医大学西京医院全军骨科研究所,陕西西安710032 [4]西安交通大学材料工程学院疲劳实验室,陕西西安710000

出　　处：《河北北方学院学报（医学版）》2008年第1期9-11,共3页Journal of Hebei North University:Medical Edition

摘　　要：目的:研究深低温冷冻法和常温法储骨对皮质骨生物力学特性的影响。方法:用深低温冷冻法和常温酒精浸泡法储存相同时间的股骨皮质作标本,分别将其修成弯曲及压缩试件,在Instron 1195型电子拉伸试验机上测试两组的极限弯曲强度,弹性模量及极限压缩强度,所得数据进行组间t检验。结果:两组间极限弯曲强度、弹性模量、极限压缩强度差异均不明显(P>0.05)。结论:深低温冷冻及常温法储骨对皮质骨生物力学特性无影响,在无深低温冷冻储骨条件的地方,如有合适的骨源,也可积极取骨用常温法储存,以免骨源浪费。Objective： To Study the cryopreservation and room temperature preservation＇s effect to the biomechanics characteristics of the cortical bone. Methods： Preserve the thighbone＇s cortical bone with the cryopreservation and the room temperature preservation, while make samples,and then turn them to be bended and compressed samples. Test the two groups＇ ultimate flexure strength,modulus of elasticity, ultimate crushing strength in the Auto Tensile Tester（Instron-l195）,then inspect the data with ＂t＂ test between the two groups. Results： The discrepancy of ultimate flexure strength,modulus of elasticity, ultimate crushing strength between the two groups was not very apparent（P〉0.05）. Conclusion： The cryopreservation and the room temperature preservation will not influnce the biomechanies characteristics of the cortical bone, so, when the bones can＇t be cryopreserved, if there is suitable source of bone, they can be preserved in the room with normal temperature to prevent them from being wasted.

关 键 词：低温保存 皮质骨 酒精 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]