缬沙坦对高血压并阵发性心房颤动患者的临床观察  

Effect of Valsartan in treatment of atrial fibrillation

作　　者：曾智[1] 何兆初[1] 易家骥[1] 何文凯[1] 

机构地区：[1]广州医学院第一附属医院心内科,510120

出　　处：《中国现代药物应用》2008年第2期19-20,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨缬沙坦对高血压并阵发性心房颤动患者的临床效果.方法将60名高血压合并阵发性房颤患者随机分成缬沙坦治疗组与氨氯地平对照组,比较24个月后维持窦性心律的情况与左房大小等参数变化。结果治疗组维持窦性心律的情况优于对照组,两组差异有统计学意义(P<0.05);治疗组左房结构功能改善优于对照组,差异有统计学意义(P<0.05)。结论缬沙坦对高血压并阵发性心房颤动患者的维持窦性心律及改善左房功能有一定的帮助。Objective This paper is to observe the effect of Valsartan in treatment of hypertensive patients with atrial fibrillation. Methods 60 patients with atrial fibrillation were included in the study and randomly divided into two groups. The trial group were treated with Valsartan and the control group were treated with Amlodipine. The duration of observation was up to two years, we Compared the two groups with the rate of sinus rhythm and changes in left atrial function. Results After two years of follow-up, there was a significant difference between the two groups. The rate of sinus rhythm in trial group was higher than the control group and improvement of left atrial function in the trial group was better than the control group. Conclusion Valsartan can reduce the occurrence of atrial fibrillation in hypertensive patients and improve left atrial function.

关 键 词：高血压 房颤 缬沙坦 左房结构功能 

分 类 号：R544.1[医药卫生—心血管疾病] R541.75[医药卫生—内科学]