血清肌钙蛋白T判断急性心肌梗塞溶栓后血管再通  

JUDGEMENT OF REPERFUSION OF ACUTE MYOCARDIAL INFARCTION AFTER THROMBOLYTIC THERAPY BY TROPONIN T

作　　者：吴彦[1] 于祥志 徐成斌[1] 蒋宝琦[1] 陈红[1] 李彤妹[1] 祁瑞环[1] 

机构地区：[1]北京医科大学人民医院心内科,100044 [2]黑龙江省建三江中心医院

出　　处：《北京医科大学学报》1997年第4期352-354,共3页Journal of Peking University(Health Sciences)

摘　　要：目的：评价肌钙蛋白T（TnT）判断急性心肌梗塞（AMI）溶栓再通的敏感性和特异性。方法：酶联免疫法测定52例AMI病人溶栓后血清心肌特异性TnT的变化，与CK、CKMB及冠脉造影等进行比较。结果：所有病例TnT均显著升高；以TnT高峰时间≤发病16h和TnT12h／24h比值＞1．0做为血管再通标准，其敏感性分别为84．2％和86．8％，特异性为78．6％，准确性分别为82．7％和84．6％。结论：TnT做为溶栓后血管再通的指标，具有较高的敏感性和特异性。Objective: To Observe the sensitivity and specificity of Troponin T(TnT) on the judgement ofreperfuion of acute myocardial infarction (AMI) after thrombolytic therapy. Methods: Serum cardiac TnTwas detected by enzyme linked immunoassay in 52 AMI patients of thrombolysis, and compared with CK,CKMB and coronary angiography. Results: TnT was increased in all patients. If the reperfusion criteria wasTnT peak time ≤16 h after onset of AMI and TnT12 h/24 h> 1. 0, the sensitivity was 84. 2 % and 86. 8 %,the specificity was 78. 6 %, the accuracy was 82. 7 % and 84. 6 %. Conclusion: The judgement of reperfusionby TnT has high sensitivity and specificity.

关 键 词：肌钙蛋白 诊断 心肌梗塞 药物疗法 

分 类 号：R542.22[医药卫生—心血管疾病]