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作 者:李灿[1] 黄道生[1] 杨剑刚[1] 朱伟光[1] 何明大[1]
出 处:《中药新药与临床药理》2008年第1期70-72,共3页Traditional Chinese Drug Research and Clinical Pharmacology
基 金:"八五"国家科技攻关项目(85-919-03-02-01)
摘 要:目的验证救心复脉注射液治疗厥脱的临床疗效及安全性。方法将150例患者随机分为两组。治疗组100例,用救心复脉注射液治疗;对照组50例,用多巴胺注射液治疗。结果救心复脉注射液治疗厥脱的临床总疗效与对照组比较无统计学意义(P>0.05);对轻度厥脱和感染性休克的疗效优于对照组(P<0.05);用药后10~30min厥脱主症积分及血压改善优于对照组(P<0.05);且对肝、肾功能、血、尿常规无明显影响,未见明显不良反应。结论救心复脉注射液治疗厥脱安全有效。Obejective To verify the therapeutic effect on syncope- collapse syndrome treated by Jiuxin Fumai Injection (JFI). Methods One hundred and fifty patients were divided into two groups randomly: the treatment group ( n = 100) was treated with JFI, and the control group with dopamine Injection ( n = 50). Results There were no significant differences in the clinical total effective rates between the two groups ( P 〉 0. 05) ; the therapeutic effect on slight syncope - collapse syndrome and septic shock is superior to the control group ( P 〈 0.05) ; after medication for 10 - 30 minutes, the scores of main symptoms of syncope - collapse syndrome and the amelioration of blood pressure is superior to the control group ( P 〈 0. 05) . The results of safe investigation showed that JFI had no obvious impact on hepatic function or renal function , nor on blood routine or urine routine. No obvious adverse effect was found. Conclusion JFI is safe and effective for the treatment of syncope - collapse syndrome.
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