东莨菪碱在家猪基础麻醉中对心率的控制  

Effect of Scoplamine on Heart Rate at Basic Anesthesia in Pig

作　　者：刘凡[1] 吴金凤[1] 谢瑞芹[1] 崔炜[1] 郝玉明[1] 李保华[1] 

机构地区：[1]河北医科大学第二医院心内科,石家庄050000

出　　处：《中国比较医学杂志》2008年第1期37-38,共2页Chinese Journal of Comparative Medicine

基　　金：河北省自然科学基金(301366)

摘　　要：目的评价东莨菪碱在不使用呼吸机家猪基础麻醉中对心率、血压的影响。方法与结果48头家猪分为东莨菪碱组和山莨菪碱(654-Ⅱ)组,基础麻醉后两组心率、收缩压、舒张压分别为532.08±105.67 ms与394.17±59.78 ms,157.00±18.26 mmHg与178.63±20.73 mmHg,118.63±16.51 mmHg与128.21±17.00 mmHg,两组比较有统计学差异。结论东莨菪碱作为家猪的基础麻醉用药,对心率血压的影响较654-Ⅱ小。Objective To evaluate M-agonist, scoplamine and anisodamine＇s effect in heart rate, blood pressure and anesthetic amount during animal experiment. Method and Results Scoplamine and anisodamine were used before anaesthesia in pig. In group of scoplamine, heart rate, blood pressure war lower than the group of anisodamine （532.08 ± 105.67 ms vs 394.17 ± 59.78 ms, 157.00±18.26 mmHg vs 178.63 ± 20.73 mmHg, 118.63 ± 16.51 mmHg vs 128.21 ± 17.00 mmHg, P 〈0.05）. Conclusion Scoplamiue is better than anisodamine in control heart rate and blood pressure in pre-operation in pigs.

关 键 词：东莨菪碱 山莨菪碱 心率 血压 家猪 

分 类 号：R544.204[医药卫生—心血管疾病]