应用声学定量技术评价高血压病患者左室舒张功能的临床研究  

Evaluation of left ventricular diastolic function in patients with hypertension by acoustic quantification technique

作　　者：刘表虎[1] 朱向明[1] 李国杰[1] 李劲[1] 张霞[1] 

机构地区：[1]皖南医学院附属矶山医院超声科,芜湖市241001

出　　处：《临床超声医学杂志》2008年第1期13-15,共3页Journal of Clinical Ultrasound in Medicine

基　　金：安徽省自然科学基金(03043714);安徽省临床医学重点学科技术进步专项基金(20042034)

摘　　要：目的探讨声学定量分析技术评价高血压病患者左室舒张功能的价值。方法高血压病患者48例,对照组20例。根据左室心肌质量指数将高血压病患者分为无左室肥厚组最与左室肥厚组。声学定量分析技术测量左房充盈分数(AFF)、左室快速充盈期峰值率(PRFR),并与传统评价左室舒张功能的二尖瓣口舒张期血流频谱E峰(VE)、A峰(VA)、VE/VA,二尖瓣环运动频谱e峰(Ve)、a峰(Va)及Ve/Va进行比较。结果随着高血压病病程加重,AFF逐渐升高,而PRFR逐渐减低;左室肥厚组最为明显,与无左室肥厚组及对照组比较,差异有显著性意义(P<0.05)。结论声学定量参数AFF、PRFR可以评估早期左室舒张功能,是一种无创、快速、准确的新参数。Objective To evaluate left ventricular diastolic function in patients with hypertension by acoustic quantification technique（AQ）. Methods Twenty normal subjects and forty- eight patients with hypertension were examined by echocardiography. Hypertensive patients were divided into two groups according to left ventricular mass index （LVMI） ： left ventricular hypertrophy （LVH） group, no left ventricular hypertrophy （NLVH） group. Left atrial filling fraction （AFF） and left ventricular peak rapid filling rate （PRFR） were measured by AQ and compared with peak VE,VA,VE/VA,Ve,Va,Ve/Va. Results With the increase of hypertension, AFF gradually increased, while PRFR gradually reduced, which was obvious in left ventricular hypertrophy group. Compared with NLVH group and the control group, there were significant differences （ P 〈0.05）. Conclusion AQ was useful to the early assessment of diastolic dysfunction in hypertensive heart disease. AFF and PRFR may be potential parameters to evaluate LV diastolic performance.

关 键 词：超声心动描记术 高血压病 心功能 

分 类 号：R581.1[医药卫生—内分泌]