睡眠鼾症患者131例多导睡眠图分析  

Polysomnographic analysis of 131 sleeping-snorers

作　　者：梁海燕[1] 任寿安[1] 李富莲[1] 

机构地区：[1]山西医科大学第一医院呼吸科,太原030001

出　　处：《山西医科大学学报》2008年第1期52-54,64,共4页Journal of Shanxi Medical University

摘　　要：目的探讨多导睡眠图和动态SaO2监测在临床诊断阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的意义及体重指数(BMI)对OSAHS患者睡眠质量和SaO2的影响。方法主诉睡眠打鼾患者131例,根据夜间多导睡眠图(PSG)监测结果分为4组,即单纯鼾症组、轻度、中度、重度OSAHS组。对PSG监测指标进行组间比较,对睡眠呼吸暂停低通气指数(AHI)和SaO2(%)相关指标、BMI和PSG监测指标作直线相关分析。结果①102例被诊断为不同程度的阻塞性睡眠呼吸暂停低通气综合征(OSAHS),四组间每小时呼吸暂停+低通气数、累计数、累计时间、AHI、SaO2≥3%的脱饱和度次数和SaO2≤90%时间比例比较有统计学差异。②所有患者AHI和SaO2相关指标呈显著负相关,和BMI呈显著正相关,睡眠期最低SaO2和BMI呈显著负相关。结论使用PSG对OSAHS进行诊断及病情判断须结合AHI和睡眠期最低SaO2;每小时呼吸暂停或/和低通气数、累计数、累计时间、AHI是OSAHS诊断和分度的可靠指标;SaO2≤90%时间占睡眠总时间的比例为单纯动态SaO2监测OSAHS提供诊断和分度的参考指标;肥胖是导致SAHS的重要危险因子,BMI可作为睡眠呼吸暂停的一个重要判断指标。Objective To investigate the role of polysomnography and nocturnal dynamic oximetry in diagnosis of obstructive sleep apnea hypopnea syndrome（OSAHS）, and the value of body mass index （BMI） for evaluating sleep quality and oxygen saturation in patients with OSAHS. Methods One hundred and thirty-one patients suffering from snoring were divided into 4 groups： primary snoring（PS） group, mild, moderate and severe OSAHS groups. The parameters of ~ were compared among 4 groups. The correlations between apnea hypopnea index（AHI） and correlative parameters of SaO2 （ % ）, between BMI and parameters of PSG were analyzed. Results ①One hundred and two cases were diagnosed as OSAHS. There was significant difference among 4 groups in the frequency of apnea and hypopnea, duration of apnea, duration of hypopnea, AHI, the number of oxygen desaturation ≥3% and the percentage of time spent at SaO2 below 90 %. ②AHI was negatively correlated with SaO2 values, but positively with BMI in all patients. BMI was negatively correlated with SaO2 minimum values in all patients. Conclusion AHI and SaO2 minimum values should be combined for diagnosing OSAHS and estimating state of an illness . The frequency of apnea and hypopnea, duration of apnea, duration of hypopnea and AHI are reliable parameters in diagnosing OSAHS, while the percentage of time spent at SaO2 below 90% is a reference index. Obesity could be a risk factor in result of OSAHS. BMI may be regarded as a diagnois value in OSAHS.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 多导睡眠图 血氧饱和度 体重指数 

分 类 号：R444[医药卫生—诊断学]