0．75％布比卡因和0．75％左旋布比卡因用于术后硬膜外止痛的观察  

A Clinical Comparison of 0.75% Bupivacaine and 0.75% Levobupivacaine in Epidural Analgesia After Operation

作　　者：肖丽[1] 耿华[1] 张洁[1] 罗镇国[1] 

机构地区：[1]西安市红十字会医院麻醉科,710054

出　　处：《美中国际创伤杂志》2007年第4期16-17,共2页U.S.Chinese International Journal of Traumatology

摘　　要：目的：比较0．75％布比卡因和0．75％左旋布比卡因用于术后硬膜外止痛的的镇痛效果与安全性。方法：选择ASA分级Ⅰ～Ⅱ级下肢手术接受术后硬膜外镇痛的病人50例，随机分为2组：A组（n=25）用0．75％布比卡因；B组（n=25）用0．75％左旋布比卡因行术后硬膜外自控镇痛，观察患者12h、24h和48h的镇痛效果、镇痛满意程度、各组药物需求量（PCA按压次数×0．5ml）以及有关的副作用。结果：两组均可达到完善的镇痛效果，均无剧痛病例，B组药物需求量（PCA按压次数×0．5m1）多于A组（P〈0．05），均未见局麻药毒性反应和并发症。结论：0．75％布比卡因用于术后硬膜外镇痛，其镇痛效果优于0．75％左旋布比卡因。Objective： To compare the effects and safety of 0.75% Bupivaciane and 0.75% Levobupivacaine in epidural analgesia after operation. Methods： 50 ASA Ⅰ-Ⅱ adults scheduled for lower extremities surgery were divided into two groups. Group A and B （25 cases in each group） received 0.75% Bupivacaine and 0.75% Levobupivacaine respectivly for PCA. To observe the analgesia effects, satisfactory degree, dosage （times of PCA pressed ~0.Sml） and side effects at 12h,24h and 48h after operation. Results： There was no difference between the two groups in the analgesia effects. No toxic reaction and complications were observed in all cases. But the dosage （times of PCA pressed×0.5ml） in group B was more than that in group A （P〈0.05）. Conclusion： The analgesia effect of 0.75% Bupivacaine is superior to that of 0.75% Levobupivacaine.

关 键 词：0.75%布比卡因 0.75%左旋布比卡因 硬膜外镇痛 

分 类 号：R614[医药卫生—麻醉学]