冠心病伴左室收缩功能减退患者的心率变异性分析  

Analysis of Cardiac Rhythm Variability in Patients with Coronary Artery Disease Combined with Decrement of Left Ventricular Systolic Function

作　　者：朱雅琴[1] 黄震华[2] 杨菊贤[2] 汤政德[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院心肺功能科,上海市200011 [2]上海交通大学医学院附属第九人民医院心内科

出　　处：《中国全科医学》2007年第24期2038-2039,共2页Chinese General Practice

摘　　要：目的探讨冠心病(CAD)伴左室收缩功能减退患者的心率变异性(HRV)的特征及临床价值。方法将63例CAD患者分为A、B两组,A组为左室射血分数(EF)<50%的CAD患者30例,B组为EF≥50%的CAD患者33例;另选择健康对照者31例(对照组),进行24h动态心电图监测,获得HRV各项时域指标并进行分析。结果A组、B组与健康对照组的SDNN、SDANN、SDNNI间差异均有显著性意义(P<0.01);A组和B组的SDNN、SDANN间差异有显著性意义(P<0.01),SDNNI间差异无显著性意义(P>0.05)。A组、B组与健康对照组的rMSSD、PNN50间差异均无显著性意义(P>0.05)。结论CAD尤其是CAD伴左室收缩功能减退患者的HRV明显降低。Objective To investigate the characteristics and clinical value of cardiac rhythm variability （ CRV ） in patients with coronary artery disease （CAD） combined with decrement of left ventricular systolic function. Methods 24 -hour dynamic ECG monitoring was carried out on 63 patients with CAD, who were divided into group A （n = 30, EF 〈 50% ） and group B （n =33, EFt〉50% ）. 31 normal subjects were chosen as control group. The various indexes of time domain in HRV were achieved and analyzed. Results Group A and group B were significantly different from the control group in SDNN, SDANN and SDNNI （ P 〈 0. 01 ） ; There was significant difference in SDNN and SDANN between group A and group B （ P 〈 0. 01 ）, but no significant difference was examined in SDNNI between them （ P 〉0. 05） ; Group A and group B were not significantly different from the control group in rMSSD and PNN50 （ P 〉 0. 05 ）. Conclusion HRV is obviously reduced in patients with CAD, especially in those who are combined with decrement of left ventricular systolic function.

关 键 词：冠心病 左室收缩功能减退 心率变异性 

分 类 号：R541.4[医药卫生—心血管疾病]