血液净化疗法在救治重症急性中毒中的应用  

Blood Purification Therapy in Severe Acute Toxicosis:A Study of Application

作　　者：刘付捷[1] 陈贤[1] 黄访英[1] 钟清[1] 陈康裕[1] 黄玉英[1] 

机构地区：[1]广东省湛江市广东医学院第二附属医院,524003

出　　处：《中国全科医学》2007年第24期2069-2070,共2页Chinese General Practice

摘　　要：目的探讨血液净化疗法在救治重症急性中毒患者中的作用。方法选取60例重症急性中毒患者,4例采用腹膜透析,11例采用血液透析,44例采用血液灌流,1例采用血液灌流串联血液透析。结果60例患者中,腹膜透析组昏迷1例,治疗清醒时间为透析后48.0h;血液透析组昏迷1例,治疗清醒时间为透析后48.0h;血液灌流组昏迷22例,治疗清醒时间为灌流后0.5~48.0h。治愈59例,1例乐果中毒患者死于有机磷毒性反跳。结论血液净化疗法可提高重度药物、毒物中毒的抢救成功率。昏迷患者血液灌流后清醒快,且本法易于床边操作,值得临床推广。Objective To investigate the application of blood purification therapy in severe acute toxicity. Methods Among sixty subjects with severe acute poisoning, 4 were treated with peritoneal dialysis （ PD）, 11 with hemodialysis （ HD）, 44 with hemoperfusionor （HP） and 1 with both hemoperfusion and hemodialysis. Results Among the sixty, one case with coma in PD group was treated to consciousness within 48.0 hours after treatment ; One case with coma in HD group within 48.0 hours; 22 cases with coma in HP group within 0. 5 - 48.0 hours. 59 cases healed completely; One case with rogor poisoning died of organophosphorus toxicity rebound. Conclusion Cure rate can be raised by blood purification, and HP is easy to operate and efficient in the treatment of toxicity of drug and poison.

关 键 词：中毒 血液透析滤过 治疗 

分 类 号：R459.52[医药卫生—治疗学]