垂体前叶功能减退症21例临床分析  

Hypofunction of Anterior Pituitary:Clinical Analysis of 21 Cases

作　　者：黄文平[1] 陈丽君[1] 王昱[1] 金文波[1] 徐娜[1] 

机构地区：[1]河南省南阳市中心医院内分泌科,473000

出　　处：《中国全科医学》2007年第24期2087-2089,共3页Chinese General Practice

摘　　要：目的总结垂体前叶功能减退症的临床表现和诊疗方法。方法回顾性分析21例垂体前叶功能减退症患者的临床表现及诊疗情况。结果21例均有明显乏力;20例有纳差、腹胀,时有恶心、呕吐、畏寒、少汗、智力减退、动作迟缓、体质虚弱、面色苍白,低体温,严重时虚脱、昏迷,劳动力明显减退,甚至丧失;18例低血压;17例贫血;16例无阴毛、腋毛,低血钠;13例低血糖;5例精神失常;5例昏迷;3例男性有性功能障碍;1例皮肤、巩膜轻度黄染。患者因其症状就诊于妇科、血液科、神经内科等科室。休克及不能进食者,给予葡萄糖氯化钠注射液、氢化可的松、泼尼松治疗;低血糖者给予高渗性葡萄糖注射液治疗,于糖皮质激素治疗5~7d后加用左旋甲状腺素片;年轻女性行人工月经周期治疗,男性患者适当补充雄性激素。结论垂体前叶功能减退症的临床表现差异较大,一些重要的症状、体征易被医生忽视。Objective To summarize the clinical manifestation of hypofunction of anterior pituitary. Methods A retrospective analysis was carried out on clinical manifestation and diagnosis of hypofunction of anterior pituitary. Results We were aware of distinct fatigue in 21 cases; Loss of appetite, flatulence, sometimes nausea or vomiting, hyphidrosls, intelligence degeneration, action retardation and pale faces were found in 20 cases, and collapse, coma and decrement of labour ability appeared when serious; 18 cases were with hypotension; 17 cases with anemia; 16 cases without pubes and hireus; 13 cases with hypoglycemia; 5 cases with lunacy; 5 cases with coma; 3 male cases with sex disorders; One case with slight skin and sclera xanthochromia. Cases with shock were given glucose saline, hydrocortisone and prednisone. Those with hypoglycemia received hypertonic glucose and glucocorticoid, and then levothyroxine 5 ~ 7 days later. Young women were given treatment of artificial menstrual cycles. The male patients were treated with androgen. Conclusion As there are great differences in clinical manifestations of hypofunction of anterior pituitary, many important symptoms and signs are easy to he neglected.

关 键 词：垂体功能减退症 产后出血 症状和体征 

分 类 号：R584.2[医药卫生—内分泌]