国内9家医院铜绿假单胞菌消毒剂-磺胺耐药基因的研究  

Detection of the antiseptic-sulfadiazine-resistance gene qacE△1-sulI in Pseudomonas aeruginosa in China

作　　者：王春新[1] 王继东[2] 蔡培泉[1] 过毅[1] 糜祖煌[1] 

机构地区：[1]南京医科大学附属无锡第一医院,无锡214002 [2]江南大学附属医院无锡市第五人民医院,无锡214073

出　　处：《中国抗生素杂志》2007年第12期733-735,共3页Chinese Journal of Antibiotics

基　　金：南京医科大学科技发展基金资助项目(NY0584)

摘　　要：目的调查临床分离铜绿假单胞菌消毒剂-磺胺耐药基因qacE△1-sulI的存在情况。方法收集国内9家医院临床分离的311株铜绿假单胞菌,采用PCR法检测qacE△1-sulI基因。结果311株铜绿假单胞菌196株检出qacE△1-sulI基因,总检出率为63.0%。9家医院铜绿假单胞菌qacE△1-sulI基因检出率有较大差异。结论9家医院临床分离铜绿假单胞消毒剂-磺胺耐药基因qacE△1-sulI携带率高。Objective To investigate the distribution of the antiseptic-sulfadiazine-resistance gene qacE△1-sulI in Pseudornonas aeruginosa isolated from nine hospitals in China. Methods qacE△1-sulI gene were detected by PCR methods in 311 clinical strains of Pseudornonas aeruginosa collected from the hospitals. Results 196 of 311 isolates were positive for qacE△1-sulI gene （63.0~） and the positive rates were diverse in the hospitals. Conclusion The study showed that the positive rate of qacE△1-sulI gene was high and diverse in clinical isolates of Pseudomonas aeruginosa in China.

关 键 词：消毒剂 磺胺 耐药基因 铜绿假单胞菌 

分 类 号：R378.991[医药卫生—病原生物学] R378.911[医药卫生—基础医学]