抑癌基因ING家族研究进展  

Advances in Research on Tumor Suppressor Genes ING Fimily

作　　者：蔡丽敏[1] 孙建方[1] 

机构地区：[1]中国医学科学院中国协和医科大学皮肤病研究所,南京210042

出　　处：《生物技术通报》2008年第1期65-68,共4页Biotechnology Bulletin

摘　　要：ING家族是近些年才被发现一个侯选肿瘤抑制基因家族,因其家族成员广泛参与基因转录的调控、细胞增殖、凋亡、细胞衰老、接触抑制、DNA损伤修补及抑制血管形成等,和肿瘤的发生发展密切相关而受到关注。ING（inhibitor of growth）family has emerged as strong candidate tumor suppressor genes in recent years,which its members fimctions in regulation of genes transcription,cell profiferation,apoptosis,contact inhibition,DNA repair and angiogenesis. ING family is followed with interest due to its role on tumorigenesis and progression.

关 键 词：ING 肿瘤抑制基因 细胞周期 凋亡 DNA损伤修补 基因转录 

分 类 号：Q343[生物学—遗传学]