烷基取代三唑硫酮席夫碱的合成和生物活性研究  

Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl)Schiff Bases

作　　者：孙晓红[1] 陶燕[1] 刘源发[2] 贾婴琦[2] 陈邦[2] 杨建武[1] 

机构地区：[1]西北大学化工学院化学研究所,西安710069 [2]西北大学化学系,西安710069

出　　处：《有机化学》2008年第1期155-159,共5页Chinese Journal of Organic Chemistry

基　　金：陕西省自然科学基金(No．2001H11)资助项目

摘　　要：用5-烷基-4-氨基-2,4-二氢-1,2,4-三唑-3-硫酮与取代芳醛在酸催化下反应合成了7个席夫碱,化合物结构用^(1)H NMR,IR和元素分析进行了表征,对植物病原菌的生物活性测试表明它们具有较好的生物活性.Seven Schiff bases have been prepared by an acid catalyzed condensation of 5-alkyl-4-amino- 2,4-dihydro-1,2,4-triazole-3-thione with substituted aromatic aldehydes, the structures of which have been confirmed by ^1H NMR, IR spectra and elemental analysis. Their biological activities to several vegetable pathogens have been tested, showing that they exhibited good fungicidal activities.

关 键 词：三唑硫酮 2 4-二氢-1 2 4-三唑-3-硫酮 合成 生物活性 

分 类 号：TQ450.2[化学工程—农药化工]