旋转磁场中加导磁材料后其磁场分布研究  

The Magnetic Flux Density Research in Three Dimension with Super-paramagnetic Material in Center

作　　者：熊平[1] 董萍[1] 郭萍[2] 

机构地区：[1]中南大学信息物理工程学院生物医学工程研究所,湖南长沙410083 [2]南华大学数理学院核物理系,湖南衡阳421001

出　　处：《中国医学物理学杂志》2008年第1期469-472,共4页Chinese Journal of Medical Physics

基　　金：国家自然科学基金资助项目(No.30371626)

摘　　要：目的:根据靶向治疗的原理,利用外加磁场引导磁性药物至肿瘤部位并滞留,分析在靶部位处外加导磁材料后磁场的分布。方法:建立纳米铁受力的物理模型。用ANSYS软件进行了磁场分布的模拟。结果:导磁材料附近磁场强度明显增强,并且与周围组织的磁场强度差别很大,纳米铁可以高效的聚积于此处。结论:旋转磁场及导磁材料有助于放射性纳米铁核素在肿瘤部位的聚集,减少体内其它部位的残留,提高靶向治疗的效果。为今后的研究奠定了基础。Objective： Using the thesis of magnetic drug targeting system, drug attracted to the tumor site for a period by external magnetic field. Magnetic field distribution was analysis in target site with super paramagnetic material near tumor site. Method： Construct the physical model of nano iron movement. Magnetic field distribution was simulated with the software of ANSYS. Result： Magnetic field near super paramagnetic material have augment significantly, and have show contrast with surrounding tissue. Nano iron can be trapped here in high efficient. Discussion： Rotate magnetic field and super paramagnetic material are good equipment in trapping nano iron to tumor site and minimum trapping in other site. All of this can make a good therapeutic effect and make foundation for further research.

关 键 词：肿瘤 靶向治疗 ANSYS软件 引导磁场 

分 类 号：R3[医药卫生—基础医学]