布地奈德治疗急性会厌炎  

Budesonide in the treatment of acute epiglottitis

作　　者：于健[1] 王立冬 薛桂芬[1] 

机构地区：[1]哈尔滨医科大学附属第一医院耳鼻咽喉科,黑龙江哈尔滨150001 [2]黑龙江省哈尔滨市第四医院耳鼻咽喉科,黑龙江哈尔滨150026

出　　处：《中国耳鼻咽喉头颈外科》2008年第1期55-56,共2页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的研究布地奈德治疗急性会厌炎的疗效。方法选择78例急性会厌炎患者,随机分成两组,分别给予雾化吸入布地奈德和地塞米松,其他治疗基本相同,统计治疗结果。结果布地奈德组有效率为98%(41/42),显效率为95%(40/42);地塞米松组有效率为81%(29/36),显效率为72%(26/36);两组间有效率差异具有显著性意义(P=0.03556),显效率差异具有极显著性意义(P=0.00498)。结论雾化吸入布地奈德治疗急性会厌炎起效快,局部抗炎作用强,能快速减轻会厌水肿,减少气管切开的几率。OBJECTIVE To explore the curative effect of budesonide on acute epiglottitis. METHODS Seventy-eight patients with acute epiglottitis were devided into 2 groups randomly. Budesonide and dexamethasone were breathed in respectively with other treatments being the same. The results were processed statistically. RESULTS The effective and apparent effective rate were 98 % and 95 % in the experimental group, 81% and 72 % in control group. The effective rate was significantly different between the 2 groups, the apparent effective rate was very significantly different between the 2 groups. CONCLUSION The budesonide is more powerful than dexamethasone in the treatment of acute epiglottitis. It can decrease the epiglottis edema more quickly and reduce the opportunity of tracheotomy.

关 键 词：会厌炎 布地奈德 气道阻塞 气管切开术 

分 类 号：R767.5[医药卫生—耳鼻咽喉科] R725.622.5[医药卫生—临床医学]