万汶与贺斯应用于急性高容量血液稀释的效果比较  

Comparation of Effect of Acute Hypervolemic Hemodilution with VOLUVEN and HES

作　　者：徐加刚[1] 刘振国[1] 田刘军[1] 牟爱珍[1] 

机构地区：[1]山东省潍坊市人民医院麻醉科,261041

出　　处：《中国误诊学杂志》2008年第5期1014-1015,共2页Chinese Journal of Misdiagnostics

摘　　要：目的:探讨万汶与贺斯应用于急性高容量血液稀释(AHH)临床效果。方法:择取手术患者40例,随机均分为万汶组和贺斯组,在术前分别输入万汶、贺斯各15 ml/kg,观察稀释前(T0)、稀释后20 min(T1)、稀释后1 h(T2)、手术结束时(T3)的HR、CVP、MAP及化验Hb、Hct、凝血、电解质和血气分析等。并记录术中出入量。结果:2组术中出入量、HR、MAP、CVP、凝血、血气指标、电解质指标在组间和组内均无显著性。2组Hb、Hct随输液量的增加而渐下降,T1、T2与T0比较均有显著性(P<0.05),2组之间的下降无显著性。结论:万汶、贺斯应用于AHH安全有效,二者之间无明显差异。Objective：To investigate the effects of acute hypervolemic hemodilution（AHH）witn VOLUVEN and HES. Methods ： Forty patients were randomized to two groups ： VOLUVEN group and HES group. Before operating, VOLUVEN or HES were infused at the rate of 15 ml/kg,30 ml/min. HR,CVP,MAP,Hb,Hct ,blood coagulation,arterial blood gas and electrolytes were recorded respectively at the times of before AHH （T0）, 20 rain after AHH （T1）, 1 h after AHH （T2） and at the end of operation （T3）. The volume of infusion,blood loss, blood transfusion and urine were recorded during the operating. Results ： The volume of infusion, urine,and blood loss remained, HR, MAP, CVP, blood coagulation,arterial blood gas and electrolytes unchanged significantly between two groups. Hb and Hct were significantly decrease during study in T1 ,T2 compare with T0,There were no changes between two groups. Conclusions ： AHH With VOLUVE and HES can safely be applied to the patient, there are no significant between two groups.

关 键 词：随机对照试验[文献类型] 血液稀释 血浆代用品 人类 

分 类 号：R977.8[医药卫生—药品]